In the last few decades, a number of studies have explored the possibility of using estradiol-based contraceptives to treat menopausal symptoms such as hot flushes and vaginal dryness [
,
]. One of the main advantages of using estradiol-based contraceptives is that they are not restricted by the same contraindications and contraindications as the standard oral contraceptive, such as the use of estradiol-based pills and the use of hormonal contraceptives. Moreover, they are more convenient than the conventional oral contraceptive, such as the use of oral forms of estradiol and progestin in the same form (Table
).
However, the use of estradiol-based contraceptives is associated with an increased risk of certain types of cancers, including breast and endometrial cancers, which may be exacerbated by the use of these hormonal contraceptives [
The increased risk of these cancers is considered to be related to the use of estradiol-based contraceptives. These cancers are a group of disorders that are more common in the elderly and women. They have been reported to be more prevalent in the United States than other parts of the world, such as Asia, Africa, and South America [
The risk of breast cancer has also been reported to be increased in women who use estradiol-based contraceptives. Some authors have reported that the risk of breast cancer increased with higher doses of estradiol-based contraceptives than with the oral contraceptive, such as the use of the oral form of progesterone and the use of estrogen-only pills [
These findings are in line with those of a study conducted on the effect of using the estradiol-containing oral contraceptive on the risk of breast cancer [
Another study reported an increased risk of breast cancer in women who use the oral contraceptive, including the use of the oral form of estradiol and the use of the hormonal contraceptive progestin. The risk of breast cancer has been reported to be higher in the long-term use of oral contraceptives, such as the use of the long-acting estrogen-alone pill or the long-acting progestin-only pill, compared to the use of the hormonal contraceptive alone [
In the present study, we aimed to evaluate the risk of breast cancer among the women who used the oral contraceptive, including the long-term use of the oral contraceptive (
), and the long-term use of the oral contraceptive (
This was a single-center, double-blind, placebo-controlled study conducted in 20 women with a mean age of 65 years and a body mass index (BMI) of 27.7 kg/m2, who received at least one treatment with a progestogen-only or the long-term use of an oral contraceptive, including the long-term use of the oral contraceptive (
) for at least one year (
All subjects were asked to stop using their oral contraceptive for at least one week prior to the study, and they were asked to continue using the oral contraceptive for the duration of the study. The study was conducted according to the principles of the Declaration of Helsinki and was approved by the Institutional Review Board of the School of Medicine of Dong-IHU University of Medical Sciences. This study was carried out in accordance with the recommendations of the Declaration of Helsinki and its later amendments. The study was performed in accordance with the recommendations of the The Clinical Trial Registry of Dong-IHU University of Medical Sciences and was approved by the Ethics Committee of Dong-IHU University of Medical Sciences. All patients provided written informed consent to participate in the study.
In the study, the mean age of the subjects was 65 years, with a mean BMI of 27.7 kg/m2 and a mean duration of use of the oral contraceptive (
All participants were White, with a median age of 68 years. The median duration of use of the oral contraceptive (
), the mean duration of use of the long-term use of the oral contraceptive (
), and the mean duration of use of the oral contraceptive (
) was 17.
Alternate Name:Estrace
Description:Yuvafem is a prescription medicine prescribed for the treatment of vaginal symptoms of menopause. Estradiol topical is the generic version of Yuvafem. The estimated price of Yuvafem is approximately $144 for a supply of 8, 10 mcg vaginal tablets. Use our LowerMyRx savings offer to get an average Yuvafem discount of up to 80% at participating pharmacies near you.
Dosage Form:Box
Administration Route:Into the vagina
Drug Class:Endocrine-Metabolic Agent, Female Reproductive Agent
Generic Available:Yes
Strength:10 MCG
Warnings:Pregnancy after menopause is not likely, but if you think you could be pregnant, tell your doctor. This medicine could harm an unborn baby. Tell your doctor if you are breastfeeding, or if you have kidney disease, asthma, diabetes, edema, endometriosis, epilepsy, migraine headaches, porphyria, lupus, thyroid problems, heart disease, high blood pressure, high cholesterol, hereditary angioedema, bone problems, or a history of cancer. Tell your doctor if you had liver problems caused by pregnancy or estrogen. Tell your doctor if you have any problems with your vagina or in your pelvic area, including prolapse. Tell your doctor if you are having a surgery that requires inactivity for a long time. This medicine may cause the following problems: Increased risk of heart attack, stroke, or blood clotsIncreased risk of endometrial, breast, ovarian, or uterine cancerPossible risk of dementia (especially in women 65 years of age or older)Gallbladder diseaseEye or vision problemsHigh blood pressureHigh cholesterol or fats in the blood Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Sudden and severe stomach pain, nausea, vomiting Swelling in your hands, ankles, or feet Unusual vaginal bleeding, spotting, discharge, or itching Vision changes
Food Warnings:Some medicines can affect how estradiol works. Tell your doctor if you are using carbamazepine, clarithromycin, erythromycin, itraconazole, ketoconazole, phenobarbital, rifampin, ritonavir, St John's wort, or thyroid medicines., Do not eat grapefruit or drink grapefruit juice while you are using this medicine., Ask your doctor before you use other products or medicines in your vagina. You may need to remove the ring first., Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine before surgery or if you need to be on bed rest., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
itzerlandEstrace XL
Estrogen topical is a treatment for menopausal symptoms in women that is used alone or in combination with other therapies. It is especially useful in the treatment of early-onset vaginal atrophy. In some women, the use of estradiol topical may be necessary. Follow the directions on the label. In women over 55 years of age, the dosage of estradiol topical is 10 mg/day to 20 mg/day in a once-weekly or once-daily basis, as prescribed by a specialist. In most cases, estradiol topical is given in the form of a cream, patch, ointment, ointment, or ointment. Some medicines may cause side effects, such as decreased sex drive and erectile dysfunction. In the case of estradiol topical, discontinue use and ask your doctor about alternative treatments.
Estrace Vaginal Cream is a vaginal cream that contains the same active ingredient, Estradiol. It is used to treat vaginal symptoms such as burning and itching caused by menopause, but it does not have any estrogen-like effects.
It is available in the following strengths:
Estradiol Vaginal Cream is a topical estrogen cream that is used to treat menopausal symptoms, such as hot flashes, night sweats, and vaginal dryness. It is typically applied to the vagina every day. It is also used to treat endometriosis, a condition where a woman has trouble getting pregnant due to abnormal growths in the uterus.
It may be used during menopause (before menopause) to help prevent pregnancy and to prevent other forms of hormone-related issues such as cancer or hormone-related disorders. It may also be used to treat other conditions caused by estrogen levels in the body, such as acne.
Estradiol Vaginal Cream is available in the following strengths:
Estradiol Vaginal Cream is a vaginal cream that contains the same active ingredient, estradiol, which is absorbed through the skin.
The active ingredients of the cream are estradiol, estrone, and equilin estradiol. The recommended dosage of estradiol in this formulation is one or two tablets every day. It is usually applied to the vagina every day.
The recommended dosage of estradiol in this formulation is one tablet per day.
Estradiol Vaginal Cream should be used with a woman's diet and exercise program to help decrease estrogen levels in the body, as this may also help the estrogen levels in the body decrease.
It is also recommended to use estradiol cream as directed by your doctor, as it may be more effective when used in conjunction with a healthy balanced diet.
Estradiol Vaginal Cream is a topical estrogen cream that is applied to the vagina every day. The recommended dosage of estradiol cream is one or two tablets per day.
The recommended dosage of estradiol in this formulation is one or two tablets per day.
Estradiol Vaginal Cream should be used with a woman's diet and exercise program to help decrease estrogen levels, as this may help the estrogen levels in the body decrease.
It is also recommended to use estradiol cream as directed by your doctor, as it may be more effective when used in conjunction with a healthy diet and exercise program.
It may be recommended to use estradiol vaginal cream as directed by your doctor, as it may be more effective when used in conjunction with a healthy diet and exercise program.
It may also be recommended to use estradiol vaginal cream as directed by your doctor, as it may be more effective when used in conjunction with a healthy diet and exercise program.
The recommended dosage of estradiol cream in this formulation is one or two tablets per day.
The recommended dosage of estradiol vaginal cream in this formulation is one or two tablets per day.
Estrace 0.01 mg topical gel is used for the treatment of osteoporosis in postmenopausal women. It is indicated for the treatment of osteoporosis in postmenopausal women whose bone density is decreased by more than 50% with the use of a low-dose estrogen.
The gel is applied daily, beginning at the first signs and symptoms of osteoporosis. It is important to continue treatment as directed by your doctor, as some patients may experience bone loss or symptoms consistent with osteoporosis.
Allergy alert:Estradiol may cause a serious allergic reaction in people allergic to the topical form of menopause symptoms. If symptoms occur, stop use and seek medical help right away. Talk to your doctor about the safety of stopping this product. You should contact your doctor immediately if you experience joint pain or bloating while using the gel.
Do not use estradiol 0.01 mg Topical Gel:right before or simultaneously with a heavy meal, as this may affect the effectiveness of the gel and cause stomach bleeding.
right after application and for at least 4 weeks after stopping the treatment.
Stop use, contact your doctor and seek medical help right away if your symptoms have not improved after using the gel. Some common side effects of the gel include breast enlargement, tenderness, pain, and nipple discharge. If you notice other side effects such as dizziness, fatigue, or joint pain, contact your doctor.
Some common side effects of the gel include breast enlargement, tenderness, or swelling.
Estradiol is a form of the female hormone estrogen that may cause breast enlargement. The active ingredient in Estradiol 0.01 mg Topical Gel is Estradiol, which may cause breast enlargement (especially in postmenopausal women). Other ingredients may also be included in the gel, such as:
Estradiol 0.01 mg Topical Gel should not be used in women with a known hypersensitivity to Estrace or any of its components.
Estradiol 0.01 mg Topical Gel is contraindicated in women who are pregnant or may become pregnant because of an impaired ability to get pregnant. Women who are breastfeeding should avoid using Estradiol 0.01 mg Topical Gel.
The side effects of the gel are similar to those of other topical preparations, except that the side effects are more likely to be reversible. If any of the side effects persist or worsen, contact your doctor, especially if the side effects are more severe or do not go away, get medical help right away.
Contact your doctor if you notice other effects not listed here. These include:
Contact your doctor immediately if you experience a change in vaginal discharge, or pain or bleeding during intercourse.
If Estradiol is used for more than 4 weeks, stop treatment and discuss the risks and benefits with your doctor.
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